Transcription

(to the tune of “Frosty the Snowman”)

Copyright © 2011 Kevin Ahern

I am very pleased that David Simmons has made a professional recording of this song (complete song downloadable HERE) and others can be downloaded HERE. You will need to unzip the file to release the MP3. I am providing all songs for free download, but hope you will support this effort by purchasing my Metabolic Melody albums or calendar at the URLs at the bottom of the lyrics to this song.

Phos-pho-di-esters

Are the bonds of RNA

That support a ribopolymer

Made of G,C,U and A

The RNA polymerase

Binds to a TATA box

And copies from the template strand

All the along the way it walks

IN-i-ti-a-tion

Of transcription thus proceeds

From the closed to open complexing

In the DNA it reads

The sigma factor gets released

Its work is over fast

Polymerase can then advance

After this step has been passed

In elongation

The polymerizing spree

Moves along the way in fits and starts

Synthesizing five to three

The RNA is floppy and

It dangles from one end

Oh that’s a most important thing

For you to comprehend

Then termination

Fin-ish-ES the RNAs

Thanks to protein rho or hairpin forms

That release polymerase

So this describes transcription’s steps

In three part harmonies

Here’s hoping with this melody 

You (can) learn it all with ease

Complete list of Metabolic Melodies HERE

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