Good Protein Synthesis
(To the tune of "Good King Wenceslaus")
Copyright © 2011 Kevin Ahern
I am very pleased that Mr. David Simmons has made a professional recording of this song (complete song downloadable HERE) and others can be downloaded HERE. You will need to unzip the file to release the MP3. I am providing all songs for free download, but hope you will support this effort by purchasing my Metabolic Melody albums or calendar at the URLs at the bottom of the lyrics to this song.

Amino acids cannot join

By themselves together

They require ribosomes

To create the tether

All the protein chains get made

‘Cording to instruction

Carried by m-R-N-A

In peptide bond construction

Small subunit starts it all

With initiation

Pairing up two RNAs

At the docking station

Shine Dalgarno’s complement

In the 16 esses

Lines the A-U-G up so

Synthesis commences

Elongation happens in

Ribosomic insides

Where rRNA creates

Bonds for polypeptides

These depart the ribosome

Passing right straight through it

In the tiny channels there

Of the large subunit

Finally when the sequence of

One of the stop codons

Parks itself in the A site

Synthesis can’t go on

P-site RNA lets go

Of what it was holding

So the polypeptide can

Get on with its folding

Complete list of Metabolic Melodies HERE

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