N-A-D
(To the tune of "Penny Lane")
Copyright © 2004 Kevin Ahern
I am very pleased that Mr. Tim Karplus has made a professional recording of this song (more to come!). A downloadable MP3 of this song can be downloaded HERE and others can be downloaded HERE. You will need to unzip the file to release the MP3. This song is also contained on the new Metabolic Melodies CD available for sale HERE.
Instructor Sings
In the catabolic pathways that our cells employ
Oxidations help create the ATP
While they lower Gibbs free energy
Thanks to enthalpy
If a substrate is converted from an alcohol
To an aldehyde or ketone it is clear
Those electrons do not disappear
They just rearrange very strange
Everyone sings
N-A-D is in my ears and in my eyes
Help-ing mol-e-cules get oxidized
Voila! N-A-D-H
Instructor Sings
And the latter is a problem anaerobically
‘Cause accumulations of it muscles hate
They respond by using pyruvate
To produce lactate
Which the Cori cycle handles trans-hepatically
Synthesizing sugar’s almost effortless
Using glu-co-ne-o-gen-e-sis
Anabolic’ly, Eagerly
Everyone sings
N-A-D is in my ears and in my eyes
Help-ing mol-e-cules get oxidized
Voila! N-A-D-H