Glucagon is Coming Around
(To the tune of "Santa Claus is Coming to Town")
Copyright ©2004 Kevin Ahern

I am very pleased that Tim Karplus has made a professional recording of this song (more to come!). A downloadable MP3 of this song can be downloaded HERE and others can be downloaded HERE. You will need to unzip the file to release the MP3. This song is also contained on the new Metabolic Melodies CD available for sale HERE.

Instructor sings
You’ve gotta admire
What molecules do
Their cellular fire
Is ready on cue
Glucagon is coming around

If hormone should bind
Receptor outside
G proteins find
G nucleotides
Glucagon is coming around

Everyone sings
They activate cyclases
That make cAMPs
Which bind to Protein Kinase A
And pull the R’s from C’s

Instructor sings
The glycogen shrinks
In liver quite fast
The glucose into
Your bloodstream is passed
Thanks to this you have energy

And muscles uptake
The glucose in turn
Obtaining a substrate
All of them burn
Thanks to this you have energy

Everyone sings
The pool of phosphatidyl
Inositides in you
Can send two separate signals
When they get split in two

Instructor sings
The muscles contract
When calcium’s free
Lowering levels
Of Creatine-P
Now you’re gonna need energy

Everyone sings
Those little calcium ions
I hope you’ve learned them well
Are just like Martha Stewart
All locked up in a cell

Instructor sings
This story’s complete
I know it’s a load
My hope is your head
Ain’t gonna explode
You will need it in finals week

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