En-er-gy
(To the tune of Let It Be)
Copyright ©2002 Kevin Ahern

I am very pleased that Mr. Tim Karplus has made a professional recording of this song (more to come!). A downloadable MP3 of this song can be downloaded HERE and others can be downloaded HERE. You will need to unzip the file to release the MP3. This song is also contained on the new Metabolic Melodies CD available for sale HERE.

Instructor Sings
When I was walking through the forest
Grizzly bears came after me
So I was badly needing
En-er-gy

My body dumped some epinephrine
Out into the blood for me
'Cause I was badly needing
En-er-gy

Everyone sings
En-er-gy / En-er-gy
En-er-gy / En-er-gy
I was badly needing
En-er-gy

Instructor Sings
The epinephrine gave a kick to
Enzymes deep inside of me
To make a bunch of cyclic
AMP

And when this hit my protein kinase
Catalytic ecstasy
The C subunits started
Adding P's

Everyone sings
Adding P's, adding P's
Adding P's, adding P's
Phosphorylation city
Adding P's

Instructor Sings
The protein kinase put a phosphate
Onto PBK for me
Using energy from
ATP

And PBK in turn converted
'b's to 'a's and 'I's to 'D's *
So I released a ton of
G1P

Everyone sings
G1P / energy
G1P / energy
California needs some
G1P

Instructor Sings
And when the chaos had subsided
I consumed some Frito Lays
Which soon began reversing
These pathways

The glucose halted epinephrine
Insulin began the race to
Turn on Phosphoprotein
Phosphatase

Everyone sings
Phosphatase - cleaves the P's
Phosphatase - cleaves the P's
The dephosphorylation
Cleaves the P's

Instructor Sings
And so they were removed from action
Cellular kinases
Thanks to Phosphoprotein
Phosphatase

I'll end my story here before I
Get depressed from one last fact
That dephosphorylation
Favors fat

Everyone sings
Favors fat, favors fat
Favors fat, favors fat
Dephosphorylation
Favors fat.

Return to other Metabolic Melodies